Paul C. Langley, Ph.D., Adjunct Professor College of Pharmacy, University of Minnesota, MN
It has been demonstrated conclusively that value and utility preference scores have only ordinal properties. That means, as has been pointed out on numerous occasions, that quality adjusted life year (QALY) is a mathematically impossible construct. Continue here .
Paul C. Langley, Ph.D., Adjunct Professor, College of Pharmacy, University of Minnesota, MN
The purpose of this commentary is to focus on the downside of assumption-driven simulation modeling, the potential creation of a multitude of competing models, the mathematically impossible quality adjusted life year (QALY) and the failure to observe the axioms of fundamental measurement in mapping ordinal EQ-5D-5L preferences from the ordinal Quantitative Myasthenia Gravis Continue Here
Paul C. Langley, Ph.D., Adjunct Professor, College of Pharmacy, University of Minnesota, MN
Should decision making in health care, notably in respect of the allocation of resources between individuals and disease states, rest on notions of the burden of disease and denial of care as assessed by societal evaluations or on the extent to which the need of patients and caregivers is fulfilled. Continue here .